New Step by Step Map For thr77 login
New Step by Step Map For thr77 login
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The antibody is from purified rabbit serum by affinity purification through sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
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Overexpression of this gene is observed in several tumors, which ends up in chromosome instability, and thus may add to tumorigenesis. This protein was located to associate with, and become involved with, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in mobile-cycle controlled histone gene expression and plays a vital role in selling cell-cycle development from the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinctive isoforms, are already described. Two more splice variants had been reported but specific nucleotide sequence details is not still accessible.
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Blocking peptides are peptides that bind precisely towards the focus on antibody and block antibody binding. These peptide typically is made up of the epitope identified via the antibody.
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This guidebook outlines additional probable optimization of mobile and immunoassay parameters to be sure the best possible results are...
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This guideline outlines even more doable optimization of mobile and immunoassay parameters to guarantee the very best effects are...
Antibodies sure to the blocking peptide no more bind to your epitope to the focus on protein. By comparing the staining from your blocked antibody compared to the antibody alone, one can see which staining is unique.
Concentrate on Facts Cyclin E belongs to your hugely conserved cyclin loved ones, whose associates are characterized by a dramatic periodicity in protein abundance from the cell cycle. Cyclins perform as regulators of CDK kinases. Diverse cyclins show unique expression and degradation styles which contribute to the temporal coordination of each and every mitotic function. Cyclin E types a posh with and features as being a regulatory subunit of CDK2, whose exercise is necessary for mobile cycle G1/S transition. This protein accumulates in the G1-S section boundary and is also degraded as cells progress by S stage.
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both equally antibodies...
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